Depends on the size of the stream, and difficulty to get to. The smaller/harder it is, the more I am liable to be devastated if I see another vehicle. Because I would probably leave.
I made a long drive with Taco to some small water last summer. We got there and there was a camp set up. Panic started to set in. Fortunately, 2 of the people were at the camp and said everyone was fishing downstream and upstream was open (or the other way around, can't remember). Don't know what we would have done if they hadn't been there, maybe guessed and hoped. But we might have just left. Some of the places, run hopping just won't work due to cover, bank type, etc. Sucks sometimes, but it's part of the deal if you fish semi-remote.